Grandfather playing with granddaughter in the park

Arthritis Innovation Corporation

Accelerating Recovery After Knee Replacement

F14 is a First-in-Class intra-articular anti-inflammatory designed to reduce post-operative inflammation and the pain it causes following total knee replacement (TKR).

Because recovery means more than pain relief.

Our Mission

Science Driven by Unmet Needs

Despite major advances in orthopedic surgery, many patients undergoing total knee replacement continue to experience significant pain, inflammation, and delayed functional recovery. Current standard of care analgesia is primarily designed to reduce pain in the immediate post-operative period, but does little to address the underlying inflammation that can impair recovery in the following weeks and months.

At AIC, we are developing non-opioid, long-acting injectable therapies designed to address the biological drivers of post-surgical inflammation and improve both pain and function.

Physical therapist treating a patient's knee after total knee replacement

Product Development

A Single First-in-Class Program for a Major Orthopedic Need

F14

Post-TKR Pain and Functional Recovery

PreclinicalPhase 1Phase 2Phase 3NDA / Approval

Status

Phase 3 Active

The Opportunity

Partner with AIC

We are actively engaging with strategic partners and investors who share our conviction that non-opioid post-surgical therapies are one of the most important unmet needs in orthopedics.

Arthritis Innovation Corporation

Pioneering breakthrough therapies for TKR patients

Important Notice: This website contains forward-looking statements regarding Arthritis Innovation Corporation's pipeline and clinical programs. These statements involve risks and uncertainties. Past performance is not indicative of future results. This content is for informational purposes only and does not constitute an offer to sell or solicitation of an offer to buy any securities.

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